| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD244 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Goat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | lyophilized |
|---|
| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Immunohistochemistry: 5-15 µg/mL, Western Blot: 0.1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD244 Polyclonal Antibody. CD244 (2B4, SLAMF4) is a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via CD244 is thought to modulate NK-cell cytolytic activity. CD244 interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in the pathology of this autoimmune disease. Diseases associated with CD244 dysfunction include rheumatoid arthritis and lymphoproliferative syndrome. Alternatively splice |
|---|
| Immunogen | n/a |
|---|
| Other Names | 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, NK cell activation inducing ligand NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, h2B4, natural killer cell receptor 2B4 |
|---|
| Gene, Accession # | Entrez: 18106; Uniprot: Q07763 |
|---|
| Catalog # | PA5-47054 |
|---|
| Price | |
|---|
| Order / More Info | CD244 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|