| 产品详情 |
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| Antigenic Specificity | C8orf4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | C8orf4 Polyclonal Antibody. This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |
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| Immunogen | n/a |
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| Other Names | TC1; TC-1; Thyroid cancer protein 1 |
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| Gene, Accession # | Entrez: 56892; Uniprot: Q9NR00 |
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| Catalog # | PA5-76196 |
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| Price | |
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| Order / More Info | C8orf4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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