| 产品详情 |
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| Product Name | Manumycin A |
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| Description | MW: 550.64. Purity ≥96% by HPLC. Background: An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC?? = 30 nM). Does not affect geranylgeranyltransferase (GGTase) (IC?? = 180 uM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19 uM).uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [NSC-622141; UFC 1C] |
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| Gene, Accession, CAS # | CAS: 52665-74-4 |
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| Catalog # | MBS842786 |
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| Order / More Info | Manumycin A from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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