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| Antigenic Specificity | ANK1 / Ankyrin, N-Terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA (1:10000 - 1:100000), WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ANK1 / Ankyrin Antibody (N-Terminus) LS-C41714. Recognizes erythroid ankyrin (ankyrin-1), also known as ankyrin R or erythrocyte ankyrin. Ankyrin 1 is a 1881 amino acid ~220kD cytoplasmic protein forming an attachment for a number of integral membrane proteins and cytoskeletal elements. Ankyrin-1 contains a large number of repeats, a domain and two domains. Multiple isoforms of ankyrin-1 are generated by alternative splicing and promoter usage,is expected to recognize all erythrocyte isoforms of ankyrin-1 but is not expected to recognize the N-terminally truncated muscle isoforms of ankyrin-1. Additionallyis likely to cross react with ankyrin-1 from chimpanzee (Pan troglodytes) and lowland gorilla (Gorilla gorilla gorilla). Most ankyrins are composed of 3 structural domains; a N-terminal regulatory domain containing multiple ankyrin repeats, a central spectrin binding domain and a C-terminal regulatory domain. Ankyrin-1 is present in erythrocytes and has also been found in brain and muscle. Mutations in erythrocytic ankyrin-1 are associated with hereditary spherocytosis. |
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| Immunogen | Synthetic peptide corresponding to the amino acids 1 - 11 of the native protein conjugated to Keyhole Limpet Hemocyanin. |
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| Other Names | ANK1, ANK-1, Ankyrin-1, Ankyrin-R, Erythrocyte ankyrin, ANK, Ankyrin, Ankyrin 1, erythrocytic, SPH2, SPH1 |
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| Gene, Accession # | ANK1, Gene ID: 286 |
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| Catalog # | LS-C41714 |
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| Price | |
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| Order / More Info | ANK1 / Ankyrin, N-Terminus Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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