| 产品详情 |
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| Product Name | SI-2 |
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| Description | Purity >98%. SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). It has been shown to selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells through direct physical interactions with SRC-3. SI-2 induces death in various breast cancer cells with IC50 values of 3-20 nM without affecting normal cell viability. At 2 mg/kg, SI-2 can also inhibit primary tumor growth and reduce SRC-3 protein levels in an MDA-MB-468 breast cancer mouse model. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1E)-1-(2-pyridinyl)-ethanone-2-(1-methyl-1H-benzimidazol-2-yl)hydrazone, EPH 116 |
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| Gene, Accession, CAS # | CAS: 380537-35-9 |
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| Catalog # | LS-H9921 |
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| Order / More Info | SI-2 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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