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| Product Name | SIAH1, 90-282aa, Human, His tag, E Coli |
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| Description | MW: 24.1 kDa (216aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. E3 ubiquitin-protein ligase SIAH1, also known as SIAH1, is a member of the seven in absentia homolog (SIAH) family. SIAH1 is a tumor suppressor protein that is expressed in intestinal epithelium and activated during apoptosis. SIAH1 contains an N-terminal RING-finger domain, which is required for proteolysis, and a cystein-rich C-terminal domain, which regulates oligomerization and SIAH binding to target proteins. SIAH1 is kn |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [E3 ubiquitin-protein ligase SIAH1; SIAH1A] |
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| Gene, Accession, CAS # | SIAH1, Gene ID: 6477, Accession: NP_003022 |
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| Catalog # | MBS204247 |
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| Order / More Info | SIAH1, 90-282aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hu G., et al. (1999) Mol Cell Biol. 19: 724-732; Matsuzawas S., et al. (1998) EMBO J. 17: 2736-2747. |
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