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| Product Name | PARP1, 662-1014aa, Human, E Coli |
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| Description | MW: 39.6 kDa (354aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. PARP1 is a nuclear DNA-binding zinc finger protein which can exist as a homo- or hetero-dimer, and is strongly activated by DNA strand breaks. This protein involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP1 also plays a role in other cellular processes, including cell proliferation and differentiation. PARP-1 deficiencies lead to chromosom |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Poly (ADP-ribose) polymerase family member 1; ADPRT; ADPRT1; pADPRT; pADPRT-1; PARP; PARP-1; PPOL; Poly (ADP-ribose) polymerase family; member 1 ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase); ADPRT 1; msPARP; NAD (+) ADP ribosyltransferase 1; pADPRT 1; PARP 1; PARP1; Poly (ADP ribose) polymerase 1; poly (ADP ribose) synthetase; poly (ADP ribosyl)transferase; Poly[ADP ribose] synthetase 1; sPARP 1; sPARP1.] |
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| Gene, Accession, CAS # | PARP1, Gene ID: 142, Accession: AAH37545 |
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| Catalog # | MBS203554 |
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| Order / More Info | PARP1, 662-1014aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Dantzer F., et al. (1998) Nucleic Acids Res. 26 (8):1891-8. ; Li Y., et al. (2006) Mol Cell Endocrinol. 257-258:35-46. |
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