| 产品详情 |
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| Product Name | Platelet-Derived Growth Factor subunit B, active (PDGFB), Recombinant, Human |
| Description | Purity ≥97% as determined by SDS-PAGE and HPLC. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity). (ECO:0000250). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 3ng/ml, corresponding to a specific activity of 3.3x10e5 IU/mg. |
| Size | 2ug, 10ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PDGF subunit B, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis, Becaplermin |
| Gene, Accession, CAS # | PDGFB_HUMAN, SwissProt: P01127 |
| Catalog # | 348201 |
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| Order / More Info | Platelet-Derived Growth Factor subunit B, active (PDGFB), Recombinant, Human from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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