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| Product Name | COTL1, 1-142aa, Human, His tag, E Coli |
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| Description | MW: 18.1 kDa (162aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. COTL1 is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. COTL1 Binds to F-actin in a calcium-independent manner and has no direct effect on actin depolymerization. Recombinant human COTL1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purif |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Coactosin-like protein; CLP; FLJ43657; MGC19733] |
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| Gene, Accession, CAS # | COTL1, Gene ID: 23406, Accession: NP_066972 |
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| Catalog # | MBS203932 |
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| Order / More Info | COTL1, 1-142aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Rakonjac M., et al. (2006) Proc Natl Acad Sci u S A. 103 (35):13150-5. ; Provost P., et al. (2001) Biochem J. 359 (2):255-63.; |
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