| 产品详情 |
| Edit |   |
| Product Name | Ceruloplasmin, Mouse (Cp) |
| Description | Highly Purified (~95%). Ceruloplasmin (Cp) is a plasma metalloprotein synthesized and secreted by the liver. Cp (also known as ferroxidase; iron (II):oxygen oxidoreductase, EC 1.16.3.1) is a blue alpha-2-glycoprotein that binds 90 to 95% of plasma copper and has 6 or 7 cupric ions per molecule. It is involved in peroxidation of Fe(II) transferrin to form Fe(III) transferrin. Human Cp is a single polypeptide chain (1065aa, 135kD; chromosome 8q21.13-q23.1) structurally similar to factors V and VIII. Cp also has abundant expression in specific populations of glial cells within the brain. Hereditary Cp deficiency have profound iron accumulation in most tissues. Cp -/- mice showed no abnormalities in cellular iron uptake but a striking impairment in the movement of iron out of reticuloendothelial cells and hepatocytes. Cp may play an essential physiologic role in determining the rate of iron efflux from cells with mobilizable iron stores. Source: Ceruloplasmin, from mouse serum Applications |
| Size | 25ug |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 208790 |
| Price | |
| Order / More Info | Ceruloplasmin, Mouse (Cp) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
| 产品资料 |
|
|