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| Product Name | TFB2M, Recombinant, Human, aa20-396, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). TFB2M is S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. This protein is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. TFB2M stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity. Source: Recombinant protein corresponding to aa20-396 from human TFB2M at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~45.8kD (401aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSM QIYLGKPSRP PHLLLECNPG PGILTQALLE AGAKVVALES DKTFIPHLES LGKNLDGKLR VIHCDFFKLD PRSGGVIKPP AMSSRGLFKN AGRFCI LGSEAATRKH LPARNHCGLS DSSPQLWPEP DFRNPPRKAS KASLDFKRYV TDRRLAETLA LGIEAVPWTA DIPLKVVGMF PSRGEKRALW KLAYDLYSCT SIYKFGRIEV NMFIGEKEFQ KLMADPGNPD LYHVLSVIWQ LACEIKVLHM EPWSSFDIYT RKGPLENPKR REL |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TFB2M, Recombinant, Human, aa20-396, His-Tag (Dimethyladenosine Transferase 2 Mitochondrial, Hkp1, mtTFB2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138757 |
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| Order / More Info | TFB2M, Recombinant, Human, aa20-396, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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