| 产品详情 |
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| Product Name | Epothilone B |
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| Description | Purity >95%. Epothilone B (Epo B) is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis. It induces mitotic arrest at the G2 -M transition in Hs578T and HeLa cells (IC50 = 3 and 32 nM, respectively) as well as in multidrug resistant KB3-1 and KBV-1 cells (IC50 = 16 and 92 nM, respectively). Epo B causes cell cycle arrest at nanomolar IC50 values in cell lines from ovarian, breast, lung, colon, prostate, and squamous cancer. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7S,11S-dihydroxy-8,8,10R,12S,16R-pentamethyl-3S-[(1E)-1S-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, Epo B |
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| Gene, Accession, CAS # | CAS: 152044-54-7 |
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| Catalog # | LS-H7684 |
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| Price | |
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| Order / More Info | Epothilone B from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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