| 产品详情 |
| Edit |   |
|---|
| Product Name | E-64d |
|---|
| Description | Purity >98%. Cysteine proteases are a class of enzymes containing an active-site cysteine residue that is important in protein degradation pathways E-64d, a synthetic analog of E-64 and ethyl ester of E-64c, is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases. E-64d inhibits calpain and the cysteine proteases cathepsins F, K, B, H, and L. By disrupting protease activity, E-64d, at concentrations between 20-200 µM, has been shown to arrest human epidermoid carcinoma A431 cells at mitotic metaphase. It also inhibits protease-resistant prion protein accumulation in scrapie-infected neuroblastoma cells with an IC50 value of 0.5 µM. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3-[[[(1S)-3-methyl-1[[(3S-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2S-oxiranecarboxylic acid, ethyl ester, Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281 |
|---|
| Gene, Accession, CAS # | CAS: 88321-09-9 |
|---|
| Catalog # | LS-H7612 |
|---|
| Price | |
|---|
| Order / More Info | E-64d from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|