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| Product Name | Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein |
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| Description | Fibroblast Growth Factor-21 (FGF-21) is a metabolic cytokine belonging to the heparin-binding FGF family. Along with FGF-19/15 and FGF-23, FGF-21 is categorized as a member of the atypical FGF subfamily, as it must be complexed to the Klotho co-receptor in order to bind to the FGF receptors and activate the downstream signaling pathway. In vivo FGF-21 is expressed in liver, pancreas, adipose tissue, and skeletal muscle, and it plays a central role in the energy metabolism. The expression of FGF-21 is stimulated by free fatty acids and insulin resistant states and is correlated with whole-body insulin resistance. FGF-21 activates glucose uptake in adipocytes and increases insulin sensitivity, implicating it as a novel target with potential anti-diabetic properties.Recombinant human Fibroblast Growth Factor-21 (rhFGF-21) produced in E. coli is a single non-glycosylated polypeptide chain containing 182 amino acids. A fully biologically active molecule, rhFGF-21 has a molecular mass of 19.5 kDa analyzed by reducing SDS-PAGE. Synonyms: Fibroblast Growth Factor-21, FGFL |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FGF21 |
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| Gene, Accession, CAS # | Gene ID: 26291 |
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| Catalog # | ABIN2017818 |
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| Order / More Info | Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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