| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human Collagen alpha-3(IV) chain |
|---|
| Description | 1446-1667aa; Partial. MW: 30.6kD. Purity >90% as determined by SDS-PAGE. Type IV collagen is the major structural component of glomerular basent membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. |
|---|
| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [Good pasture antigen] |
|---|
| Gene, Accession, CAS # | COL4A3, Gene ID: 1285, Accession: NP_000082.2 |
|---|
| Catalog # | MBS1265507 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human Collagen alpha-3(IV) chain from MYBIOSOURCE INC. |
|---|
| Product Specific References | Complete primary structure of the human alpha 3(IV) collagen chain. Coexpression of the alpha 3(IV) and alpha 4(IV) collagen chains in human tissues.Mariyama M., Leinonen A., Mochizuki T., Tryggvason K., Reeders S.T.J. Biol. Chem. 269:23013-23017(1994) Leinonen A.Structure of the human type IV collagen gene COL4A3 and mutations in autosomal Alport syndrome.Heidet L., Arrondel C., Forestier L., Cohen-Solal L., Mollet G., Gutierrez B., Stavrou C., Gubler M.-C., Antignac C.J. Am. Soc. Nephrol. 12:9 |
|---|
| 产品资料 |
|
|