| 产品详情 |
| Edit |   |
|---|
| Product Name | CECR2, Recombinant, Human, aa424-538, GST-tag (Cat Eye Syndrome Critical Region Protein 2) |
|---|
| Description | Purity ~95% (SDS-PAGE). The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. Cat eye syndrome critical region protein 2 (CECR2) is a transcription factor that forms a heterodimeric complex with the ATP-dependent chromatin remodeler SNF2L forming the CECR2-containing-remodeling factor (CERF). The CERF complex plays a critical role in neurulation. More recently, the bromodomain of CECR2 was shown to have strong gamma-H2AX inhibition activity su |
|---|
| Size | 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Cat Eye Syndrome Critical Region Protein 2 |
|---|
| Gene, Accession, CAS # | CECR2, Gene ID: 27443, SwissProt: Q9BXF3 |
|---|
| Catalog # | 219650 |
|---|
| Price | |
|---|
| Order / More Info | CECR2, Recombinant, Human, aa424-538, GST-tag (Cat Eye Syndrome Critical Region Protein 2) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|