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Product Name | Recombinant Human IL-13 Protein |
Description | IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Interleukin-13;IL-13;IL13;NC30; NC30 (Human), P600 (Murine) |
Gene, Accession, CAS # | IL13, UniProt: P35225 |
Catalog # | PROTP35225-3 |
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Order / More Info | Recombinant Human IL-13 Protein from BOSTER BIO |
Product Specific References | n/a |
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