| 产品详情 |
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| Product Name | T16A(inh)-A01 |
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| Description | Purity >95%. Transmembrane protein 16A (TMEM16A, also known as anoctamin-1) is a calcium-activated chloride channel (CaCC) with roles in transepithelial anion transport and smooth muscle contraction. T16A(inh)-A01 is an aminophenylthiazole that inhibits transient TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. Its inhibitory effects are independent of voltage and do not prolong the rate of TMEM16A current deactivation. T16A(inh)-A01 blocks CaCC activity in vascular smooth muscle cells and relaxes mouse and human blood vessels. It also inhibits the proliferation of pancreatic cancer and squamous carcinoma cells in culture. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]-acetamide |
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| Gene, Accession, CAS # | CAS: 552309-42-9 |
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| Catalog # | LS-H10083 |
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| Price | |
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| Order / More Info | T16A(inh)-A01 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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