| 产品详情 |
| Edit |   |
|---|
| Product Name | TAK-875 |
|---|
| Description | MW: 533.63. TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with an EC50 of 0.072 ?M. TAK-875 is a new agent applied in the treatment of type 2 diabetes. TAK-875 not only elevated the levels of intra-cellular inositol monophosphate as well as calcium contents in rat insulinoma INS-1 833/15 cells but also improved the tolerance of glucose and amplified insulin secretion when orally administered in tolerance test. However, TAK-875 didn't increase the secretion of insulin and c |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | [TAK-875] |
|---|
| Catalog # | MBS8506575 |
|---|
| Price | |
|---|
| Order / More Info | TAK-875 from MYBIOSOURCE INC. |
|---|
| Product Specific References | TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats. Tsujihata Y et al. J Pharmacol Exp Ther. 2011 Jul 13 The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans. |
|---|
| 产品资料 |
|
|