| 产品详情 |
| Edit |   |
|---|
| Product Name | A-419259 (hydrochloride) |
|---|
| Description | Purity >95%. Src family kinases are non-receptor tyrosine kinases with diverse roles in signal transduction and disease. A-419259 is an inhibitor of Src family kinases, with IC50 values for Src, Lck, Lyn, and Hck of 9, 3, 3, and 0.43 nM, respectively. It displays at least 1,000-fold selectivity for these enzymes over other kinases. A-419259 induces growth arrest and apoptosis in chronic myelogenous leukemia cell lines. It prevents differentiation while maintaining pluripotency in embryonic stem cells. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 7-[trans -4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, trihydrochloride, RK-20449 |
|---|
| Gene, Accession, CAS # | CAS: 1435934-25-0 |
|---|
| Catalog # | LS-H6351 |
|---|
| Price | |
|---|
| Order / More Info | A-419259 (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|