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| Product Name | Neuropoietin, Recombinant, Mouse (NPO, NP) |
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| Description | Purity ~98% (SDS-PAGE). Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-alpha component, gp130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human Neuropoietin gene has evolved toward a pseudogene, suggesting that the alternative signaling via CNTF is an effective compensatory pathway. Source: Recombinant protein corresponding to 183aa residues from mouse Neuropoietin, expressed in E. coli. Molecular Weight: ~19.8kD Biologi |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NPO, NP |
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| Gene, Accession, CAS # | Ctf2, Gene ID: 244218, SwissProt: P83714 |
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| Catalog # | 220100 |
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| Order / More Info | Neuropoietin, Recombinant, Mouse (NPO, NP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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