产品详情 |
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Antigenic Specificity | TPA Tissue Plasminogen Activator/PLAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100ug |
Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
Applications | Flow Cytometry, IHC-P, IHC-F, ICC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal Picoband™ antibody for PLAT detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human;Mouse;Rat. No cross reactivity with other proteins. PLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. |
Immunogen | A synthetic peptide corresponding to a sequence of human PLAT(QKDVPGVYTKVTNYLDWIRDNMRP). |
Other Names | Tissue-type plasminogen activator; t-PA; t-plasminogen activator; tPA; Alteplase; Reteplase; PLAT |
Gene, Accession # | PLAT, UniProt: P00750 |
Catalog # | A02965-1 |
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Order / More Info | TPA Tissue Plasminogen Activator/PLAT Antibody from BOSTER BIO |
Product Specific References | n/a |
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