| 产品详情 |
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| Product Name | MK-2206 |
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| Description | MW: 480.39. Purity ≥98% by HPLC. Background: A highly selective non-ATP competitive allosteric Akt inhibitor with IC??'s of 8 nM, 2 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. MK-2206 potently inhibits phosphorylation of Thr??? and Ser??? in 3T3-L1 adipocytes with IC?? values of 0.11 and 0.18 uM, respectively as well as downstream effects of insulin on GLUT4 translocation (IC?? = 0.47 uM) and glucose transport (IC?? = 0.14 uM). In addition, treatment with MK-2206 causes a robust, conc |
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| Size | 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride] |
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| Gene, Accession, CAS # | CAS: 1032350-13-2 |
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| Catalog # | MBS842880 |
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| Price | |
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| Order / More Info | MK-2206 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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