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| Product Name | Thyroid Stimulating Hormone Receptor (TSHR) ACTOne Stable Cell Line |
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| Description | Background/Introduction: TSHR is a member of the G protein-coupled receptor superfamily of integral membrane proteins and is coupled to the Gs protein. Upon binding circulating thyrotropin, a G-protein signal cascade activates adenylyl cyclase and intercellular levels of cAMP rise. cAMP activates all functional aspects of the thyroid cell, including iodine pumping; thyroglobulin synthesis, iodination, endocytosis and proteolysis; thyroid peroxidase activity; and hormone release. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [thyroid stimulating hormone receptor; Thyrotropin receptor; thyrotropin receptor; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; thyrotropin receptor-I, hTSHR-I; thyroid stimulating hormone receptor; Thyroid-stimulating hormone receptor; TSH-R] |
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| Gene, Accession, CAS # | TSHR, Gene ID: 7253, NCBI: AAR07906.1 |
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| Catalog # | MBS433661 |
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| Order / More Info | Thyroid Stimulating Hormone Receptor (TSHR) ACTOne Stable Cell Line from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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