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| Product Name | Thyroid Peroxidase, Recombinant, Human, His-Tag (TPO) |
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| Description | Purity ~95% (SDS-PAGE). Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of ~100kD molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3. Source: Recombinant protein corresponding to human TPO, a glycosylated, polypeptide chain containing 834aa, fused to 6x His-tag, expressed in Sf9 insect cells. Molecular Weight: ~92.87kD Applications: Suitable for use in ELISA and Western Blot with monoclonal anti-TPO antibody and monoclonal anti-hexa-His-tag antibody. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209235 |
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| Order / More Info | Thyroid Peroxidase, Recombinant, Human, His-Tag (TPO) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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