| 产品详情 |
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| Product Name | PX-478 hydrochloride |
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| Description | Purity >98% by HPLC. PX-478 hydrochloride is an inhibitor of HIF-1a (IC50 of 20-30 MM) with potential antineoplastic activity. PX-478 inhibits HIF-1alpha protein levels and transactivation in a variety of cancer cell lines. The inhibitory effect of PX-478 on HIF-1alpha levels is primarily due to its inhibition of translation because HIF-1alpha translation continues in hypoxia when translation of most proteins is decreased. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (S)-4-(2-amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)aniline oxide dihydrochloride |
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| Gene, Accession, CAS # | CAS: 685898-44-6 |
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| Catalog # | LS-H3744 |
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| Order / More Info | PX-478 hydrochloride from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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