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| Product Name | RND3, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest. Source: Recombinant corresponding to aa1-241 of human RND3 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS C Molecular Weight: 29.2kD (261aa) confirmed by MALDI-TOF Enzyme Activity: Not determined. This product |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RND3, Recombinant, Human (Rho-related GTP-binding Protein RhoE, Protein MemB, Rho Family GTPase 3, Rho-related GTP-binding Protein Rho8, Rnd3, ARHE, RHO8, RHOE) |
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| Gene, Accession, CAS # | Accession: NP_005159 |
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| Catalog # | R1998-13R |
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| Order / More Info | RND3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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