| 产品详情 |
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| Product Name | Recombinant Human Trichoplein keratin filament-binding protein |
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| Description | 1-498aa; Full Length. MW: 77.03kD. Purity >90% as determined by SDS-PAGE. Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mitochondrial protein with oncostatic activity; Mitostatin; Tumor suppressor protein] |
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| Gene, Accession, CAS # | TCHP, Gene ID: 84260, Accession: NP_001137324.1 |
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| Catalog # | MBS1479340 |
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| Order / More Info | Recombinant Human Trichoplein keratin filament-binding protein from MYBIOSOURCE INC. |
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| Product Specific References | Identification of trichoplein, a novel keratin filament-binding protein.Nishizawa M., Izawa I., Inoko A., Hayashi Y., Nagata K., Yokoyama T., Usukura J., Inagaki M.J. Cell Sci. 118:1081-1090(2005) Identification of trichoplein, a novel keratin filament-binding protein.Nishizawa M., Izawa I., Inoko A., Hayashi Y., Nagata K., Yokoyama T., Usukura J., Inagaki M.J. Cell Sci. 118:1081-1090(2005). A novel tumor suppressor gene at 12q (TS12Q).Baffa R., Croce C.M., Gomella L.G., Iozzo R.V., Vecchione A. |
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