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| Product Name | Factor IXa DEGR, Human |
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| Description | Purity ≥95%. Factor IXa is prepared from highly purified factor IX by activation with factor XIa, as described by Lindquist et al. (5). The factor IXa is further purified by gel filtration, followed by immuno- affinity purification. Purity is assessed by SDS-PAGE analysis. Factor IXa with the active site irreversibly blocked by the fluorescent inhibitor, Dansyl-EGRck. Activation of Factor X By Factor IXa: The intrinsic factor Xase complex consists of an enzyme, factor IXa, and a cofactor, factor VIIIa, assembled on a phospholipid surface in the presence of calcium ions. The enzyme complex proteolytically cleaves a MW 10kD activation peptide from the NH2-terminal of the heavy chain of factor X, thus expressing the active-site of factor Xa. Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid complex. The activation results from the cleavage of two peptide bonds in the factor IX molecule, relea |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | F0017-21 |
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| Order / More Info | Factor IXa DEGR, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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