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| Product Name | Ro 106-9920 |
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| Description | Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 µM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(Phenylsulfinyl)tetrazolo[1,5-b]pyridazine; |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 20712 |
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| Price | |
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| Order / More Info | Ro 106-9920 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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