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| Product Name | Chemerin, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Human Chemerin, also known as Tazarotene induced Gene 2 (TIG2), is an adipokine that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1. Its other ligands include G protein-coupled receptor 1 and chemokine receptor-like 2. Chemerin is expressed in various tissues where its biologically active form is generated by proteolytic removal of C-terminal residues by circulating proteases. In human, the soluble protoform gets processed into a monomeric, heparin binding bioactive molecule that can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Source: Recombinant protein corresponding to human Chemerin expressed in E. coli. Molecular Weight: ~16kD Biological Activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human ChemR23. The ED50 for this effect is typically 4-20ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Chemerin, Recombinant, Human (RARRES2, RAR-Responsive Protein TIG2, Tazarotene-Induced Gene 2 Protein, Retinoic Acid Receptor Responder Protein 2) |
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| Gene, Accession, CAS # | Gene ID: 5919, SwissProt: Q99969 |
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| Catalog # | 499881 |
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| Order / More Info | Chemerin, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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