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| Product Name | Interleukin-6, active (IL6), Recombinant, Human |
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| Description | Purity ≥96% as determined by SDS-PAGE and HPLC. Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. Biological Activity: Assay #1: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1ng/ml, corresponding to a specific activity of > 1.0x10e7 IU/mg. Assay #2: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation |
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| Size | 5ug, 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-6, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor |
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| Gene, Accession, CAS # | IL6_HUMAN, SwissProt: P05231 |
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| Catalog # | 348148 |
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| Order / More Info | Interleukin-6, active (IL6), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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