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| Product Name | Interleukin-21, active (IL21), Recombinant, Human |
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| Description | Purity ≥97% as determined by SDS-PAGE and HPLC. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. (ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by by a cell proliferation assay using human N1186 T cells is less than 20ng/ml, corresponding to a specific activity of 5.0x10e4 IU/mg. |
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| Size | 2ug, 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-21, |
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| Gene, Accession, CAS # | IL21_HUMAN, SwissProt: Q9HBE4 |
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| Catalog # | 348118 |
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| Order / More Info | Interleukin-21, active (IL21), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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