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| Product Name | Interferon lambda 2, Recombinant, Mouse (IFNl2, Interleukin 28A, IL-28A) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin: ≤ 1EU/1ug. IL-28A (also named interferon-L2, IFN-L2), IL-28B (IFN-L3) and IL-29 (IFN-L1) are type III interferons that are class II cytokine receptor ligands.1-4 They are distantly related to members of the IL-10 family and type I IFN family.1-4 Mouse IL-28A cDNA encodes a 193 amino acid (aa) protein with a 19 aa signal peptide and a 174 aa mature protein that lacks N-glycosylation sites. Mature mouse IL-28A shares 81% and 66% aa sequence identity with rat and human IL-28A, respectively, and functions across species.5 Mouse IL-28A and IL-28B share 97% aa identity; the mouse lacks a functional IL-29 gene.4 Type III interferons are widely expressed, but are mainly produced by antigen presenting cells in response to viruses and double-stranded RNA that interact with Toll-like receptors or RIG-1 family helicases.2-6 They signal through a widely expressed receptor that is a heterodim |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I7662-35D |
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| Order / More Info | Interferon lambda 2, Recombinant, Mouse (IFNl2, Interleukin 28A, IL-28A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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