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| Product Name | Apigenin |
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| Description | Purity >98%. Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the degradation of I?BAlpha and down-regulates NF-?B levels in WEHI-231 cells. Apigenin at 5 µM is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Chamomile, Flavone, NSC 83244, Versulin |
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| Gene, Accession, CAS # | CAS: 520-36-5 |
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| Catalog # | LS-H6564 |
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| Order / More Info | Apigenin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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