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| Product Name | GRK6, Recombinant, Human, GST-Tag (GPRK6, FLJ32135) |
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| Description | Purified (~70-90%). GRK6 is a Ser/Thr protein kinase and a member of the G protein-coupled receptor kinase subfamily. GRK6 is present in all tissues with strongest expression in placenta and skeletal muscle. GRK6 can phosphorylate proteins such as rhodopsin, ADRB2 and the leukotriene B4 receptor BLT1. GRK6 phosphorylates G protein-coupled dopamine receptors, thereby regulating their activity and mediating desensitization of the receptors. GRK6 knockout mice showed supersensitivity to the locomotor-stimulating effects of psychostimulants, including cocaine and amphetamine. Source: Recombinant protein corresponding to human GRK6 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~93kD Specific Activity: 11nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: BC017272 |
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| Catalog # | 500050 |
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| Order / More Info | GRK6, Recombinant, Human, GST-Tag (GPRK6, FLJ32135) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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