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| Product Name | GRK3, Recombinant, Human, GST-Tag (Beta-Adrenergic Receptor Kinase 2, ADRBK2, BARK2) |
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| Description | Purified (~70-90%). GRK3 or beta-adrenergic receptor kinase 2 specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. GRK3 is a member of the receptor kinase family that broadly serves to regulate receptor function. GRK3 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. GRK3 is highly expressed in lung, heart, and adipose tissue. Single nucleotide polymorphisms (SNPs) in the promoter region of GRK3 have been associated with bipolar disorder. Source: Recombinant protein corresponding to human GRK3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~84kD Specific Activity: 6nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_005160 |
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| Catalog # | 500048 |
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| Order / More Info | GRK3, Recombinant, Human, GST-Tag (Beta-Adrenergic Receptor Kinase 2, ADRBK2, BARK2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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