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| Product Name | Long[R3]IGF-I, recombinant protein (Receptor Grade) |
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| Description | Product Specifications Long[R3]IGF-I: The Product: Long[R3] insulin-like growth factor-I (Long[R3]IGF-I) is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg (R) for the Glu (E) at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus. Scientists have engineered this analog with the express purpose of increasing biological activity. Long[R3]IGF-I is significantly more potent than IGF-I in vitro and in vivo. The enhanced potency is due to the markedly decreased binding of long R3 IGF-I to all IGF binding proteins. These binding proteins normally inhibit the biological actions of IGFs.Source: Long[R3]IGF-I is produced in E. coli using a patented expression system the Long[R3]IGF-I is correctly folded and purified by several chromatography steps to yield Receptor Grade Long[R3]IGF-I.Purity: >95% (as determined by HPLC and N-terminal sequence analysis)Molecular Weight: 9111.6 daltons - confirmed by Mass SpectrometryN-terminal sequence analysis of recombinant product: 18 residues >95% single sequenceBiological Activity: (stimulation of protein synthesis in rat L6 myoblasts) ED50 <10 ng/mlEndotoxin (LAL): <0.1 EU/ugStorage/Stability: At least 2 years at 2-4°C(lyophilised)Appearance: White Powder State: Dried from 0.1 M acetic acid: under dry nitrogen @ slight vacuum (-25kPa)Reconstitution: Dissolve in dilute acid (e.g. 10mM HCl or 0.1M acetic acid), aliquot and store at -20°C. For lower dilutions (e.g.<1mg/ml) inclusion of a carrier protein is recommended. Avoid freeze-thaw cycles. This is a Gropep specification. Long[R3]IGF-I is a trademark of GroPep. ibt is authorized distributor of GroPep. |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LongTMR3 Insulin-like Growth Factor-I, Receptor Grade, recombinant |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | BU020 BU100 BM001 |
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| Order / More Info | Long[R3]IGF-I, recombinant protein (Receptor Grade) from IMMUNOLOGICAL & BIOCHEMICAL TESTSYSTEMS GmbH |
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| Product Specific References | n/a |
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