| 产品详情 |
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| Product Name | NHE1, Control Peptide, Rat (Na, H Exchanger 1) |
| Description | Highly purified. A 22aa peptide within the cytoplasmic, c-terminal domain of the rat NHE1. Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE1 (rat/mouse; 820 aa; human 815 aa; chromosome 1 p35-36.1) is 'House Keeper' an |
| Size | 100ug |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | N2015-05 |
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| Order / More Info | NHE1, Control Peptide, Rat (Na, H Exchanger 1) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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