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| Product Name | NHE6, Human (Na, H Exchanger 6, KIAA0267) (Control Peptide) |
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| Description | Highly purified. Control peptide for N2020-50 (antiserum) and N2020-55 (affinity purified antibody). Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. A mammalian homolog of yeast NHA2 has been identified and classified as |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2020-60 |
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| Order / More Info | NHE6, Human (Na, H Exchanger 6, KIAA0267) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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