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| Product Name | Calphostin C (UCN 1028C, PKF115-584, Cal-C) |
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| Description | Purity ~95% (HPLC). Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source: Cladosporium cladosporioides sp. Formula: C44H38O14 Solubility: Soluble in ethanol, methanol, DMSO or dimethylformamide. Poorly soluble in H2O. Molecular Weight: ~790.8 |
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| Size | 100ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207099 |
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| Order / More Info | Calphostin C (UCN 1028C, PKF115-584, Cal-C) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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