| 产品详情 |
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| Antigenic Specificity | CCR3, aa5-28 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, IHC-P (1:125), WB (1:500) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR3 Antibody (aa5-28) LS-C187709. Recognizes an epitope within the N-terminal (NT) region of mouse CD193, otherwise known as C-C chemokine receptor type 3 or CCR3. CD193 is a 359 amino acid ~42 kD multi pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD193 is expressed by basophils, eosinophils, microglia, Th2 cells and dendritic cells. CD193 acts as a receptor for eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5), the former being a chemoattractant for eosinophils and basophils. CD193 is involved in leukocyte chemotaxis and, along with CD191 (CCR1), is implicated as a regulator of T cell and dendritic cell interaction during the process of antigen presentation. CD193 is implicated as an activator of eosinophils in allergic lung disease, and is a useful TH2 cell marker in monitoring immune responses. Is reported as suitable for use in immunocytochemistry on acetone fixed cells. |
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| Immunogen | Synthetic peptide TDEIKTVVESFETTPYEYEWAPPC corresponding to amino acids 5-28 within the N-terminal region of mouse CD193. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster (83%). |
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| Other Names | CCR3, C-C chemokine receptor type 3, B-chemokine receptor, CD193, CD193 antigen, Chemokine c-c motif receptor 3, C-C chemokine receptor 3, CKR3, CC-CKR-3, CCR-3, CMKBR3, Eosinophil eotaxin receptor, Eotaxin receptor, C-C CKR-3, CC chemokine receptor 3 |
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| Gene, Accession # | CCR3, Gene ID: 1232 |
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| Catalog # | LS-C187709 |
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| Price | |
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| Order / More Info | CCR3, aa5-28 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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