| 产品详情 |
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| Product Name | DcR2, ID, Blocking Peptide |
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| Description | Purified 60-70%. Peptide corresponding to amino acids 249 to 263 of human DcR2 precursor (4-6). Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor (1-3). Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD (4-6). DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DcR2, ID, Blocking Peptide (TRAIL-R4, TRUNDD, Decoy Receptor2, TNF receptor related receptor for TRAIL, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRUNDD, Tumor necrosis factor receptor superfamily member 10D precursor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | D1500-05P |
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| Price | |
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| Order / More Info | DcR2, ID, Blocking Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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