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| Product Name | Recombinant Human Transcription factor SOX-2 |
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| Description | 1-317aa; Full Length. MW: 50.3kD. Purity >90% as determined by SDS-PAGE. Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic st cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural st cell self-renewal. Keeps neural cells undifferentiat |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [transcription factor SOX-2; Transcription factor SOX-2; transcription factor SOX-2; SRY-box 2] |
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| Gene, Accession, CAS # | SOX2, Gene ID: 6657, Accession: NP_003097.1 |
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| Catalog # | MBS959792 |
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| Order / More Info | Recombinant Human Transcription factor SOX-2 from MYBIOSOURCE INC. |
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| Product Specific References | The cDNA sequence and chromosomal location of the human SOX2 gene.Stevanovic M., Zuffardi O., Collignon J., Lovell-Badge R., Goodfellow P.Mamm. Genome 5:640-642(1994) Sadler L.A., Badzioch M.D., Wagner M., Graves K.A., Swaroop A., Yang-Feng T.L., Zheng K., Daiger S.P. Mutations in SOX2 cause anophthalmia.Fantes J., Ragge N.K., Lynch S.-A., McGill N.I., Collin J.R.O., Howard-Peebles P.N., Hayward C., Vivian A.J., Williamson K., van Heyningen V., FitzPatrick D.R.Nat. Genet. 33:461-463(2003) Induct |
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