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| Product Name | Interleukin 6, Recombinant, Human (IL-6) |
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| Description | Purity ≥98% by SDS-PAGE and HPLC. Endotoxin: ≤0.1ng/ug. IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Ra and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9kD protein containing 184aa residues. Biological Activity: Fully biologically active when compared to standards. The ED50 was determined by the dose dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells is ≤0.1ng/ml, corresp |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I8428 |
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| Order / More Info | Interleukin 6, Recombinant, Human (IL-6) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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