| 产品详情 |
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| Product Name | ZM-447439 |
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| Description | Purity >98% by TLC. ZM-447439 is a selective ATP-competitive inhibitor of Aurora kinase B1 (IC50 = 50 nM, Aur A IC50 = 1 uM, Aur C IC50 = 250 nM at physiological ATP concentrations, Aur A IC50 = 110nM and Aur B IC50 = 113nM). ZM-447439 did not significantly inhibit a panel of 14 other kinases including mitotic kinases CDK1 and PLK1. It prevents chromosome alignment, spindle checkpoint function and cytokinesis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide |
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| Gene, Accession, CAS # | CAS: 331771-20-1 |
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| Catalog # | LS-H14894 |
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| Order / More Info | ZM-447439 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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