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| Product Name | FG-2216 |
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| Description | Purity >98%. Hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) enzymes act as central gatekeepers of post-transcriptional and transcriptional adaptation to hypoxia, oxidative stress, and excitotoxicity. FG-2216 is an orally active PHD2 inhibitor (IC50 = 3.9 µM) that stabilizes HIF-Alpha. It has been shown to reversibly stimulate erythropoietin secretion at 100 µM in vitro and to increase hematocrit, red blood cell count, and hemoglobin levels at 50 mg/kg in mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-glycine, IOX3, YM-311 |
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| Gene, Accession, CAS # | CAS: 223387-75-5 |
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| Catalog # | LS-H7784 |
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| Order / More Info | FG-2216 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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