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| Product Name | Recombinant Human MIA Protein |
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| Description | MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis. Recombinant human MIA is a 12.2 kDa globular protein containing 108 amino acid residues including two intramolecular disulfide bonds. |
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| Size | Various Sizes |
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| Concentration | n/a |
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| Applications | Cell Culture |
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| Other Names | Melanoma-derived growth regulatory protein;Melanoma inhibitory activity protein;MIA; Melanoma Inhibitory Activity, Cartilage-derived retinoic acid-sensitive protein (CD-RAP) |
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| Gene, Accession, CAS # | MIA, UniProt: Q16674 |
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| Catalog # | PROTQ16674-2 |
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| Price | |
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| Order / More Info | Recombinant Human MIA Protein from BOSTER BIO |
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| Product Specific References | n/a |
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