| 产品详情 |
| Edit |   |
|---|
| Product Name | BHPI |
|---|
| Description | Purity >95%. BHPI is an antagonist of estrogen receptor Alpha (ERAlpha) that blocks 17Beta-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERAlpha-dependent gene expression and protein synthesis by activating the unfolded protein response in cells. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1,3-dihydro-3,3-bis (4-hydroxyphenyl)-7-methyl-2H-indol-2-one |
|---|
| Gene, Accession, CAS # | CAS: 56632-39-4 |
|---|
| Catalog # | LS-H6784 |
|---|
| Price | |
|---|
| Order / More Info | BHPI from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|