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| Product Name | TIP30, aa1-242, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Source: Recombinant corresponding to aa1-242 of human 6x HTATIP2 his tagged, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP Molecu |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TIP30, aa1-242, Recombinant, Human (30kD HIV-1 TAT-interacting Protein, CC3, FLJ26963, HIV-1 TAT-interactive Protein 2, Oxidoreductase HTATIP2, SDR44U1, HTATIP2) |
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| Gene, Accession, CAS # | Accession: AAH15358 |
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| Catalog # | T5499-86H |
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| Order / More Info | TIP30, aa1-242, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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